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Functional wellness genetics

MaxFunction

Understand your pathways. Personalize your next steps.

  • Histamine, hormones & nutrient pathways
  • Your results explained in plain English
  • Personalized nutrition & lifestyle guidance included

76 genes103 genetic variants

See genes & variants
Original price $199.00 - Original price $199.00
Original price $199.00
$199.00
$199.00 - $199.00
Current price $199.00

Average lab turnaround: 5–7 days

MTHFR, and the bigger picture

Methylation is just the beginning.

Explore the genetic pathways behind nutrient processing, histamine, hormones, antioxidants, and more. Open a topic to see what MaxFunction includes.

Compare our panels
Methylation & B vitamins19 methylation genes*MTHFR, folate & B12
  • MTHFR-related pathways
  • Folate processing and transport
  • Vitamin B12 processing
  • Methyl-donor sensitivity
Histamine pathwaysProduction & breakdownUnderstand the connections
  • Histamine metabolism
  • DAO- and HNMT-related pathways
  • Plain-English explanations of your genetic tendencies
Hormones & thyroidHormone processingThyroid conversion
  • Hormone production and binding
  • Estrogen and androgen metabolism
  • Thyroid conversion pathways
Vitamins & nutrientsHow your body processes nutrientsVitamins, choline & iron
  • Vitamins A, D and E
  • Choline and phosphatidylcholine
  • Iron metabolism
Detox & antioxidantsCellular protectionOxidative stress pathways
  • Detoxification and exposure-related genetics
  • Glutathione-related pathways
  • Antioxidant production and recycling
Brain & stressDopamine & serotoninStress-response pathways
  • Dopamine and stress-response pathways
  • Serotonin-related pathways
  • COMT- and MAO-related insights
Inflammation & fatsFatty-acid pathwaysFat metabolism
  • Inflammation-related genetics
  • Fatty-acid processing
  • Fat metabolism insights
Heart & vascularCirculation-related geneticsMore to explore in your report
  • Heart and vascular report topics
  • Clotting-related genetic findings
  • Explanations of how these genes work

*19 genes with tested variants across methylation, folate and B12 pathways, including MTHFR. Folate and B12 genes are included in this count; topics overlap. These are genetic insights, not measurements of current vitamin, hormone, or histamine levels.

See every gene & variant included

76 genes · 103 tested variants. A gene can have several tested variants. For example, we check three variants in MTHFR, and count MTHFR as one gene.

  • ACE1 variant

    rs4343

  • AHCY1 variant

    rs819147

  • ANKK11 variant

    rs1800497

    Includes the Taq1A marker often discussed with DRD2. ANKK1 is the gene counted here.

  • AOC1DAO4 variants

    rs1049742, rs1049793, rs2052129, rs10156191

  • APOE2 variants

    rs7412, rs429358

  • BCO1BCMO12 variants

    rs7501331, rs12934922

  • BDNF1 variant

    rs6265

  • BHMT1 variant

    rs3733890

  • CBS3 variants

    rs234706, rs1801181, rs4920037

  • CD3201 variant

    rs2336573

  • CLOCK1 variant

    rs1801260

  • COMT3 variants

    rs4633, rs4680, rs4818

  • CUBN1 variant

    rs1801222

  • CXCL8IL81 variant

    rs4073

  • CYP17A11 variant

    rs743572

  • CYP19A12 variants

    rs4646, rs10046

  • CYP1A11 variant

    rs1048943

  • CYP1B12 variants

    rs1056827, rs1056836

  • CYP27B11 variant

    rs10877012

  • CYP2C192 variants

    rs4244285, rs12248560

  • CYP2D63 variants

    rs16947, rs1065852, rs1135840

  • CYP2E11 variant

    rs6413432

  • CYP3A41 variant

    rs2740574

  • CYP3A51 variant

    rs776746

  • DAOA1 variant

    rs2391191

  • DBH1 variant

    rs1611115

  • DHFR1 variant

    rs1643649

  • DIO11 variant

    rs2235544

  • EPHX11 variant

    rs1051740

  • F21 variant

    rs1799963

  • F51 variant

    rs6025

  • FADS21 variant

    rs1535

  • FOLH11 variant

    rs202676

  • FOLR11 variant

    rs2071010

  • FUT21 variant

    rs601338

  • G6PD1 variant

    rs1050829

  • GCLM1 variant

    rs41303970

  • GPX11 variant

    rs1050450

  • GPX41 variant

    rs713041

  • GSTM51 variant

    rs366631

    Includes rs366631, a marker discussed with GSTM1. This entry does not imply a direct GSTM1 deletion measurement.

  • GSTP12 variants

    rs1695, rs1138272

  • HFE3 variants

    rs1799945, rs1800562, rs1800730

  • HNMT1 variant

    rs11558538

  • IL17A1 variant

    rs2275913

  • IL1B1 variant

    rs16944

  • IL61 variant

    rs1800795

  • IL6R1 variant

    rs2228145

  • MAOA2 variants

    rs6323, rs1137070

  • MAOB1 variant

    rs1799836

  • MAT1A1 variant

    rs3851059

  • MMACHC1 variant

    rs12272669

  • MTHFD11 variant

    rs2236225

  • MTHFR3 variants

    rs1801131, rs1801133, rs2274976

  • MTHFS1 variant

    rs6495446

  • MTR1 variant

    rs1805087

  • MTRR2 variants

    rs1532268, rs1801394

  • MYRF1 variant

    rs174537

    Includes rs174537 in the FADS-associated region. MYRF is the gene counted here.

  • NAT21 variant

    rs1801280

  • NOS32 variants

    rs1799983, rs2070744

  • NQO11 variant

    rs1800566

  • OXTR1 variant

    rs53576

  • PEMT2 variants

    rs7946, rs12325817

  • PON11 variant

    rs662

  • SCN1A1 variant

    rs6432860

  • SERPINE11 variant

    rs1799889

  • SHBG1 variant

    rs1799941

  • SHMT11 variant

    rs1979277

  • SLC19A11 variant

    rs1051266

  • SOD12 variants

    rs1041740, rs2070424

  • SOD21 variant

    rs4880

  • SRD5A11 variant

    rs1691053

  • SULT1A11 variant

    rs1042028

  • SUOX1 variant

    rs773115

  • TCN21 variant

    rs1801198

  • TNF2 variants

    rs1799724, rs1800629

  • VDR3 variants

    rs731236, rs1544410, rs2228570

How we count genes and variants

We test selected DNA positions in genes and associated regions; this is not whole-gene sequencing. Each named gene is counted once, even when we test multiple variants. A variant ID is counted once across report topics. We do not add extra genes for overlapping annotations or alternate names.

These totals describe the test's coverage. They are not a count of findings that will be significant for you, and some tested markers may not appear as separate rows in your report.

Family owned

Personal service from the team behind your test.

In-house genetic testing

We own, operate, and maintain our genetic testing equipment inside a CLIA-certified laboratory.

Your data is never sold

Your genetic data is never shared with third parties. Samples are destroyed after processing.

Made to make sense

Plain-English explanations with the genetic detail available when you want it.

MaxFunctionSample report · B12 pathways
Actual B12 pathway diagram from the MaxFunction sample report, connecting absorption, transport, cellular uptake, and related genes.

Actual excerpt from sample report, page 12. Example results vary by person.

See what you'll receive

Make sense of the connections.

Your report is designed for you to read and understand, with plain-English explanations, visual pathways, and personalized food and lifestyle suggestions.

Understand the pathway

Visual diagrams show how genes work together, beyond a single MTHFR result.

See your results in context

Find your genetic results alongside plain-English explanations, organized into foundational, core, and advanced sections.

Explore practical next steps

Explore personalized food and lifestyle suggestions, with clear explanations to help you decide where to start.

See your report explained, step by step →

Explore the full sample report (PDF, opens in a new tab)

From your home to your insights

A simple swab. A useful next step.

Order your kit

Your collection kit ships to your door, with instructions to get started.

Swab at home

Collect your sample with a simple cheek swab. No blood draw needed.

Send it back

Use the included prepaid return label for US orders. International kits include return instructions.

Explore your report

Average lab turnaround: 5–7 days. You'll receive an email when your report is ready.

Included with your kit: cheek swab, sample vial, collection instructions, laboratory analysis, and your personal report. US orders include a prepaid return label.

Choose the coverage that fits you

Want food & fitness insights, too?

The Works includes everything in MaxFunction, plus expanded food, nutrition, metabolism, and fitness insights.

  • Optimal diets, weight loss strategies & appetite
  • GI & digestion, gluten & dairy genetics
  • Blood sugar, exercise & recovery

Expand to The Works for $150.00 more.

Explore The Works Compare all report topics

A few helpful answers

Before you get started.

Have a question about choosing a test?
Talk with our team.

Can I understand the report on my own?

Yes. Your report is designed for you to read and understand, with plain-English explanations of your genetic findings, visual pathways, and personalized nutrition and lifestyle suggestions. You do not need a practitioner appointment to read your results. If you want extra support, you can choose to share the report with your practitioner. See how it reads in a sample report (PDF, opens in a new tab).

Does MaxFunction include MTHFR?

Yes. MaxFunction includes MTHFR-related variants and 19 genes with tested variants across methylation, folate and B12 pathways. The count includes folate and B12 genes; it is a gene count, not a count of separate topics or all variants in the panel.

Should I choose MaxFunction or The Works?

Choose MaxFunction for functional wellness topics such as methylation, histamine, hormones, antioxidants, and nutrient processing. Choose The Works if you also want expanded food, digestion, diet, weight, metabolism, and fitness insights. Compare the report topics.

What kind of sample do I provide?

A cheek swab collected at home. Your kit includes a swab, sample vial, and step-by-step instructions. Follow the collection instructions supplied in your kit.

How soon will I receive results?

Average lab turnaround is 5–7 days. You'll receive an email when your report is ready.

Does it diagnose conditions or measure current levels?

No. MaxFunction explores genetic tendencies for informational and wellness purposes. It does not diagnose disease or measure your current vitamin, hormone, or histamine levels. Consult a qualified healthcare professional before making medication or treatment changes.

Can I use Shop Pay or my HSA/FSA card?

Shop Pay payment options are displayed beneath the price and at checkout, subject to eligibility and the terms shown by Shop Pay. MaxFunction is HSA/FSA eligible; you can use your HSA or FSA card at checkout.

Is return shipping included?

US orders include a prepaid return label. Canadian and other international orders include instructions for arranging return shipping; a prepaid return label is not included.

What happens to my sample and data?

Your sample is destroyed after processing. Your genetic data is never sold or shared with third parties. Read our privacy policy for details.

Start with a clearer picture.

Functional wellness insights in one at-home DNA test.

Choose MaxFunction