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Function. Nutrition. Fitness.

Methylation is
just the beginning.

Explore what's included, see the genes behind the topics, and find the report that fits your interests.

Find what matters to you.

Open any topic for report details and tested variant examples.

33 report topics

Methylation & folateMTHFR C677T, A1298C, and G1793A variants · Folate absorption and related genesMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • MTHFR C677T, A1298C, and G1793A variants
  • Folate absorption and related genes
  • Folate transport and cellular use
  • Methyl donor sensitivity
  • Methylfolate-related guidance

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

AHCYrs819147 (both panels)BHMTrs3733890 (both panels)CBSrs1801181, rs234706, rs4920037 (both panels)MAT1Ars3851059 (both panels)MTHFRrs1801131, rs1801133, rs2274976 (both panels)MTRrs1805087 (both panels)MTRRrs1532268, rs1801394 (both panels)SHMT1rs1979277 (both panels)DHFRrs1643649 (both panels)FOLH1rs202676 (both panels)FOLR1rs2071010 (both panels)MTHFD1rs2236225 (both panels)MTHFSrs6495446 (both panels)SLC19A1rs1051266 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Vitamin B12 processingIntestinal B12 absorption · Cellular B12 uptakeMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Intestinal B12 absorption
  • Cellular B12 uptake
  • B12 transport and processing
  • Different forms of B12

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

CD320rs2336573 (both panels)CUBNrs1801222 (both panels)FUT2rs601338 (both panels)
rs492602, rs602662 (Works)MMACHCrs12272669 (both panels)TCN2rs1801198 (both panels)MTRrs1805087 (both panels)MTRRrs1532268, rs1801394 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Learning StrategiesLearning strategies for children and adults · Study habits and memory strategiesMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Learning strategies for children and adults
  • Study habits and memory strategies
  • Structured, visual, and hands-on approaches
  • Stress management and collaborative learning

The “How Do You Learn Best?” section offers learning strategies to explore. Specific suggestions vary with the report; examples include structured routines, memory activities, visual aids, and group learning.

See the explanation in the report

This row describes report content. No specific gene or variant claim has been added.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Brain Health & APOEAPOE and brain health · Cholesterol transport and neurological functionMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • APOE and brain health
  • Cholesterol transport and neurological function
  • Nutrition and lifestyle discussion

The report explains your APOE findings and related nutrition and lifestyle considerations. Genetic tendencies are one part of brain health, not a diagnosis.

Examples of tested variants

APOErs429358, rs7412 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Histamine metabolismDAO-related dietary histamine handling · HNMT-related cellular histamine handlingMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • DAO-related dietary histamine handling
  • HNMT-related cellular histamine handling
  • Histamine-related report guidance

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

AOC1rs10156191, rs1049742, rs1049793, rs2052129 (both panels)HNMTrs11558538 (both panels)MAOArs1137070, rs6323 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Thyroid conversionT4-to-T3 conversionMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • T4-to-T3 conversion

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

DIO1rs2235544 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Hormone production & bindingHormone production-related genetics · SHBG and free hormonesMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Hormone production-related genetics
  • SHBG and free hormones

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

CYP17A1rs743572 (both panels)SHBGrs1799941 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Estrogen MetabolismAromatase and estrogen conversion · 2-, 4-, and 16-hydroxyestrogen pathwaysMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Aromatase and estrogen conversion
  • 2-, 4-, and 16-hydroxyestrogen pathways
  • Catechol estrogen processing and COMT

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

CYP19A1rs10046, rs4646 (both panels)CYP1B1rs1056827, rs1056836 (both panels)COMTrs4633, rs4680, rs4818 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Androgen & DHT PathwaysDHT-related genetic pathways · SRD5A1 and 5-alpha-reductaseMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • DHT-related genetic pathways
  • SRD5A1 and 5-alpha-reductase
  • Androgen metabolism explanations

Explore the report’s androgen and DHT pathway explanations. Genetic findings do not measure current hormone levels.

Examples of tested variants

SRD5A1rs1691053 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Oxidative stress & antioxidantsOxidative stress-related genetics · Glutathione antioxidant defenseMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Oxidative stress-related genetics
  • Glutathione antioxidant defense
  • Superoxide dismutase pathways
  • Glutathione S-transferases

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

GCLMrs41303970 (both panels)GPX1rs1050450 (both panels)GPX4rs713041 (both panels)G6PDrs1050829 (both panels)GSTP1rs1138272, rs1695 (both panels)SOD1rs1041740, rs2070424 (both panels)SOD2rs4880 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Environmental exposuresAromatic hydrocarbons · InsecticidesMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Aromatic hydrocarbons
  • Insecticides
  • Phthalates and parabens
  • Glyphosate
  • BPA and plastics
  • Butadiene and benzene

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

PON1rs662 (both panels)EPHX1rs1051740 (both panels)CYP1A1rs1048943 (both panels)CYP1B1rs1056827, rs1056836 (both panels)CYP2E1rs6413432 (both panels)
rs3813867 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Iron metabolismIron-related genetic tendenciesMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Iron-related genetic tendencies

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

HFErs1799945, rs1800562, rs1800730 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Inflammation & fatty acidsInflammatory response · Omega-3-related geneticsMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Inflammatory response
  • Omega-3-related genetics
  • Omega-6 and arachidonic acid

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

IL1Brs16944 (both panels)IL6rs1800795 (both panels)IL6Rrs2228145 (both panels)TNFrs1799724, rs1800629 (both panels)FADS2rs1535 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Vitamin A conversionBeta-carotene conversion to retinolMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Beta-carotene conversion to retinol

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

BCO1rs12934922, rs7501331 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Vitamin D processingVitamin D receptor-related genetics · Vitamin D-related interpretationMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Vitamin D receptor-related genetics
  • Vitamin D-related interpretation

Both panels include VDR and CYP27B1 markers. The Works also includes GC and CYP2R1 markers and expands the vitamin D report detail.

Examples of tested variants

VDRrs1544410, rs2228570, rs731236 (both panels)CYP27B1rs10877012 (both panels)GCrs2282679 (Works)CYP2R1rs10741657 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Vitamin EVitamin E nutrition guidance · Antioxidant role and food sourcesMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Vitamin E nutrition guidance
  • Antioxidant role and food sources

Educational nutrient guidance is included in the report. This is not a dedicated vitamin E genotype result.

See the explanation in the report

This row describes report content. No specific gene or variant claim has been added.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Choline & phosphatidylcholinePEMT-related choline needs · Connection with methylationMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • PEMT-related choline needs
  • Connection with methylation

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

PEMTrs12325817, rs7946 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Vitamin B6Vitamin B6-related genetic guidanceMaxFunction: Works sectionThe Works: ✓ Included

Inside the report

  • Vitamin B6-related genetic guidance

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

NBPF3rs4654748 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

The Works sample (PDF) ↗
Vitamin CVitamin C-related genetic guidanceMaxFunction: Works sectionThe Works: ✓ Included

Inside the report

  • Vitamin C-related genetic guidance

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

SLC23A1rs33972313 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

The Works sample (PDF) ↗
Dopamine & stress responseCOMT · Dopamine receptorsMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • COMT
  • Dopamine receptors
  • Dopamine beta-hydroxylase
  • Dopamine, norepinephrine, and epinephrine-related interpretation

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

COMTrs4633, rs4680, rs4818 (both panels)DBHrs1611115 (both panels)ANKK1rs1800497 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Serotonin & neurological pathwaysMAO-A and MAO-B · Serotonin-related interpretationMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • MAO-A and MAO-B
  • Serotonin-related interpretation
  • BDNF-related genetics

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

MAOArs1137070, rs6323 (both panels)MAOBrs1799836 (both panels)BDNFrs6265 (both panels)OXTRrs53576 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Sleep & lifestyleSleep timing tendencies · Sleep and weight-related discussionMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Sleep timing tendencies
  • Sleep and weight-related discussion
  • Smoking-related genetic topics

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

CLOCKrs1801260 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Food compounds & additivesFermented foods · Tyramine-containing foodsMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Fermented foods
  • Tyramine-containing foods
  • Green tea
  • Smoked meats
  • Food dyes
  • Sulfur-containing foods

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

AOC1rs10156191, rs1049742, rs1049793, rs2052129 (both panels)HNMTrs11558538 (both panels)MAOArs1137070, rs6323 (both panels)COMTrs4633, rs4680, rs4818 (both panels)CBSrs1801181, rs234706, rs4920037 (both panels)SUOXrs773115 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Cardiovascular wellnessHeart and circulatory genetics · Clotting-related genetic markersMaxFunction: ✓ IncludedThe Works: ✓ Included

Inside the report

  • Heart and circulatory genetics
  • Clotting-related genetic markers
  • Blood-pressure-related discussion

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

ACErs4343 (both panels)
rs1799752 (Works)F2rs1799963 (both panels)F5rs6025 (both panels)NOS3rs1799983, rs2070744 (both panels)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Eating habits & tasteEmotional eating · Cravings and snackingMaxFunction: Works sectionThe Works: ✓ Included

Inside the report

  • Emotional eating
  • Cravings and snacking
  • Bitter taste
  • Sweet preference
  • Overeating
  • Fasting-related discussion
  • Carbohydrate sensitivity

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

FTOrs1121980, rs1558902, rs16945088, rs8050136, rs9939609 (Works)MC4Rrs17782313 (Works)TAS2R38rs713598 (Works)LEPRrs1137101 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

The Works sample (PDF) ↗
Diet patterns & weightDASH diet · Ketogenic dietMaxFunction: Works sectionThe Works: ✓ Included

Inside the report

  • DASH diet
  • Ketogenic diet
  • Mediterranean diet
  • Hunter-gatherer diet
  • Weight loss and dietary fat

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

PPARGrs1801282, rs3856806 (Works)FTOrs1121980, rs1558902, rs16945088, rs8050136, rs9939609 (Works)TCF7L2rs7903146 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

The Works sample (PDF) ↗
GLP-1 & Weight ManagementGLP-1 and weight-management overview · Food and lifestyle discussionMaxFunction: Works sectionThe Works: Brief overview

Inside the report

  • GLP-1 and weight-management overview
  • Food and lifestyle discussion
  • Brief discussion of GLP-1 medication response

This is a brief discussion in The Works report, not a medication-selection or dosing test. Open the sample to see exactly what is included.

See the explanation in the report

This row describes report content. No specific gene or variant claim has been added.

The Works sample (PDF) ↗
Fat & lipid metabolismSaturated fats · Monounsaturated fatsMaxFunction: Selected insightsThe Works: ✓ Included

Inside the report

  • Saturated fats
  • Monounsaturated fats
  • Triglycerides
  • HDL-related discussion

MaxFunction discusses saturated fats and APOE; The Works has an additional fats section covering triglycerides, HDL, and monounsaturated fats.

Examples of tested variants

APOA2rs5082 (Works)LIPCrs1800588 (Works)LPLrs320, rs328 (Works)PPARGrs1801282, rs3856806 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Digestive & food-related geneticsFUT2 secretor status · Gut barrier-related discussionMaxFunction: Selected insightsThe Works: ✓ Included

Inside the report

  • FUT2 secretor status
  • Gut barrier-related discussion
  • Gluten-related genetic predisposition
  • Dairy-related genetics

MaxFunction includes FUT2-related discussion on its B12 page. The Works adds a dedicated digestive section with additional markers. These genetic reports do not test for food allergies.

Examples of tested variants

FUT2rs601338 (both panels)
rs492602, rs602662 (Works)MYO9Brs2305764 (Works)HLA-DQA1rs2187668 (Works)MCM6rs4988235 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

MaxFunction sample (PDF) ↗The Works sample (PDF) ↗
Fitness performanceEndurance potential · Sprint potentialMaxFunction: Works sectionThe Works: ✓ Included

Inside the report

  • Endurance potential
  • Sprint potential
  • Peak muscle power
  • Muscle fiber tendencies
  • VO2 max-related genetics
  • Ventilatory threshold
  • Training response of VO2 max
  • High-altitude performance

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

ACTN3rs1815739 (Works)PPARGC1Ars8192678 (Works)PPARDrs2016520, rs2267668 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

The Works sample (PDF) ↗
Muscle injury & recoveryMuscle damage-related genetics · Post-exercise sorenessMaxFunction: Works sectionThe Works: ✓ Included

Inside the report

  • Muscle damage-related genetics
  • Post-exercise soreness
  • Post-exercise strength
  • Muscle injury tendencies
  • Hamstring-related genetics
  • Rotator cuff-related genetics
  • Muscle cramping

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

MMP3rs650108, rs679620 (Works)COL5A1rs12722 (Works)ACTN3rs1815739 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

The Works sample (PDF) ↗
Response to exerciseResistance training response · Exercise capacityMaxFunction: Works sectionThe Works: ✓ Included

Inside the report

  • Resistance training response
  • Exercise capacity
  • Endurance versus resistance training
  • Weight loss and exercise
  • Motivation to exercise
  • Blood pressure response
  • Blood sugar response

Shown in the linked sample reports. Genetic insights do not measure current levels or diagnose a condition.

Examples of tested variants

ADRB2rs1042713, rs1042714 (Works)PPARGC1Ars8192678 (Works)PPARDrs2016520, rs2267668 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

The Works sample (PDF) ↗
Caffeine metabolismCYP1A2-related caffeine processing · Individual differences in caffeine breakdownMaxFunction: Works sectionThe Works: ✓ Included

Inside the report

  • CYP1A2-related caffeine processing
  • Individual differences in caffeine breakdown

The Works includes a caffeine metabolism section and CYP1A2 rs762551. General caffeine advice elsewhere is not the same as this reported genetic topic.

Examples of tested variants

CYP1A2rs762551 (Works)

These are related marker examples, not a complete assay list or a claim that an entire gene is sequenced.

The Works sample (PDF) ↗

Included means report coverage. Selected insights means related coverage, with more detail in The Works. Works section means an additional dedicated report section. Brief overview means a short report discussion.

How to read this comparison

The 19-gene methylation count includes tested genes across methylation, folate and B12 pathways. These topic rows overlap; they are not counts of independent biological pathways.

A gene can have several tested variants. A report topic describes content you receive. Genetic insights do not measure your current hormone or nutrient levels. Report content and recommendations depend on applicable results and the report version.

Variant totals count distinct rsIDs in the current panels: 103 for MaxFunction and 180 for The Works. Prices use the storefront currency; shipping and taxes may apply. Last coverage review: September 2026.

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